abstract：OBJECTIVE:Case report of a 35-year-old gravida 3, para 2, at 40 + 6 weeks with massive respiratory dysfunction with need of oxygenation, requiring cesarean section. CASE REPORT:Postpartum investigations revealed pathological cardiomegaly with left ventricular failure (NYHAIV). Cardiac biopsy diagnosed postpartum dilat...

journal_title：Hypertension in pregnancy

authors： Freerksen N,Jaekel J,Menon AK,Maass N,Bauerschlag D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. METHODS:A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delive...

journal_title：Hypertension in pregnancy

authors： Tersigni C,Esposito G,Albanese A,D'Ippolito S,Sabatino G,Di Simone N,Caruso A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:This study investigated endothelin-1 (ET-1) production induced by vascular endothelial growth factor (VEGF) in two different vascular wall cell types. METHODS:We analyzed the effect of endothelin-converting enzyme-1 (ECE-1) inhibitor and tissue inhibitors of matrix metalloproteinase-2 (TIMP-2) on VEGF-induce...

journal_title：Hypertension in pregnancy

authors： Seol HJ,Oh MJ,Kim HJ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:(i) To compare the levels of soluble Fas (sFas) in the sera of patients with variable degrees of preeclampsia and in healthy gravidas; and (ii) to correlate sFas with clinical, laboratory, and Doppler parameters in preeclampsia. METHODS:Fifty patients with mild preeclampsia, 50 patients with severe preeclam...

journal_title：Hypertension in pregnancy

authors： El-Sherbiny W,Soliman A,El-Mazny A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate maternal and fetal outcome of the subsequent pregnancy of primiparous women with a history of early-onset intrauterine growth restriction (IUGR), prompting delivery before 34 weeks of gestation, without concomitant maternal hypertensive disease. DESIGN:Retrospective coho...

journal_title：Hypertension in pregnancy

authors： Evers AC,van Rijn BB,van Rossum MM,Bruinse HW

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Amino-terminal pro-brain natriuretic peptide (NT-proBNP) is synthesized in cardiac ventricles in response to volume expansion. This study evaluated NT-proBNP levels to determine the clinical correlation with the severity of hypertensive disorders complicating pregnancy. METHODS:NT-proBNP levels of 95 pregnan...

journal_title：Hypertension in pregnancy

authors： Seong WJ,Kim SC,Hong DG,Koo TB,Park IS

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To report a case of cardiac arrhythmia related to a low dose of endovenous lanatoside C. CASE REPORT:A 23-year-old pregnant woman with mitral regurgitation complicated with preeclampsia and pulmonary edema presented 2 episodes of atrial tachycardia induced by a intravenous digitalis (2 mg, IV and 1 mg, IV, r...

journal_title：Hypertension in pregnancy

authors： Roscani MG,Zanati SG,Magalhães CG,Borges VT,Matsubara BB

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Chymase, a chymotrypsin-like protease, is a non-ACE angiotensin II (Ang II) generating enzyme. We determined if maternal chymotrypsin-like protease/chymase activity was increased in women with preeclampsia (PE). METHODS:Maternal plasma was extracted from venous blood of healthy nonpregnant women, women with ...

journal_title：Hypertension in pregnancy

authors： Wang Y,Gu Y,Lewis DF,Alexander JS,Granger DN

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of ...

journal_title：Hypertension in pregnancy

authors： Shental O,Friger M,Sheiner E

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. METHODS:Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every...

journal_title：Hypertension in pregnancy

authors： Samangaya RA,Mires G,Shennan A,Skillern L,Howe D,McLeod A,Baker PN

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between the cancer antigen-125 (CA-125) and C-reactive protein (CRP) with preeclampsia and eclampsia. METHODS:The study group included 54 preeclamptic/eclamptic women, and 56 healthy pregnant women served as the control group. Mean arterial pressure (MAP) and albumin levels were...

journal_title：Hypertension in pregnancy

authors： Cebesoy FB,Balat O,Dikensoy E,Kalayci H,Ibar Y

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Oxidative stress and a generalized inflammatory state are features of preeclampsia (PE). The objective of this study was to compare the levels of products of inflammatory reaction and oxidative stress markers in patients with PE, and to determine the relationship between oxidative stress and inflammation in P...

journal_title：Hypertension in pregnancy

authors： Ouyang YQ,Li SJ,Zhang Q,Cai HB,Chen HP

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Caesarean section (CS) is one of the most frequently performed surgical procedures worldwide. Surgical variants include closure and non-closure of the peritoneum: in case of non-suturing the visceral peritoneum (VP), abnormal fluid collections such as blood clots may lead to formation of a hematoperitoneum...

journal_title：Hypertension in pregnancy

authors： Malvasi A,Tinelli A,Hudelist G,Vergara D,Martignago R,Tinelli R

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...

journal_title：Hypertension in pregnancy

authors： Karinen L,Leinonen M,Bloigu A,Paldanius M,Koskela P,Saikku P,Hartikainen AL,Jarvelin MR,Pouta A

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To measure cytokine production in ex vivo stimulated leukocyte populations of women with normal pregnancy and those with preeclampsia. METHODS:Whole blood from preeclamptic and normal pregnant women was stimulated with LPS or PMA/Ca-ionophore. The percentages of IFN gamma and IL-2, 4, and 10 producing lympho...

journal_title：Hypertension in pregnancy

authors： van Nieuwenhoven AL,Moes H,Heineman MJ,Santema J,Faas MM

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Leukocytes are activated in women with preeclampsia, but the class of leukocytes that infiltrates the maternal vasculature and, therefore, is most likely to cause vascular dysfunction is not known. METHODS:Subcutaneous fat biopsies were obtained at Cesarean section or abdominal surgery from 7 normal non-preg...

journal_title：Hypertension in pregnancy

authors： Cadden KA,Walsh SW

更新日期：2008-01-01 00:00:00

abstract：:The pathophysiology of preeclampsia (PET) implicates an inflammatory dysfunction. This study profiled this host response by challenging whole blood with lipopolysaccharide. Multiplex immunoassays determined interleukin (IL)-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12(p70), IL-13, IL-17, granulocyte/granulo...

journal_title：Hypertension in pregnancy

authors： Brewster JA,Orsi NM,Gopichandran N,Ekbote UV,Cadogan E,Walker JJ

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To identify parameters that may assist clinicians in predicting which women will develop preeclampsia (PE) after initially presenting with gestational hypertension (GH). METHODS:118 women were recruited to the study with GH or PE. They were divided into three groups based on their diagnosis at delivery- (1) ...

journal_title：Hypertension in pregnancy

authors： Davis GK,Mackenzie C,Brown MA,Homer CS,Holt J,McHugh L,Mangos G

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...

journal_title：Hypertension in pregnancy

authors： Williams VK,Griffiths AB,Carbone S,Hague WM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To assess hemodynamic and NT-proANP changes in women with chronic hypertension during pregnancy. METHODS:Stroke volume index (SI), heart rate (HR), cardiac output index (CI), systemic vascular resistance index (SVRI), pulse wave velocity (PWV), and left cardiac work index (LCWI) were measured using whole-bod...

journal_title：Hypertension in pregnancy

authors： Tihtonen K,Kööbi T,Huhtala H,Uotila J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To determine whether delivery mode influences placental chorionic plate arterial and venous vascular reactivity. METHODS:Normal term placentas were obtained after vaginal delivery or cesarean section. Chorionic plate arterial and venous function was assessed by wire myography. RESULTS:Sodium nitroprusside-i...

journal_title：Hypertension in pregnancy

authors： Mills TA,Baker PN,Wareing M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Hypertension that develops after 20 gestational weeks and is defined as pregnancy-induced hypertension (PIH). The main cause of PIH is vasoconstriction and the thickening of vascular media, which decreases vascular capacity and increases peripheral resistance. One of the theories postulated to explain this p...

journal_title：Hypertension in pregnancy

authors： Kwiatkowski S,Kwiatkowska E,Czajka R,Ciechanowski K,Kedzierska K,Bober J,Rzepka R,Golembiewska E,Chlubek D

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to quantify adiponectin levels in women with normal and hypertensive pregnancies to determine whether there is an independent association, while controlling for body fat and insulin sensitivity. METHODS:A cross-sectional study was conducted in the following categories: 12 normotensi...

journal_title：Hypertension in pregnancy

authors： O'Sullivan AJ,Kriketos AD,Martin A,Brown MA

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...

journal_title：Hypertension in pregnancy

authors： Bryant AS,Seely EW,Cohen A,Lieberman E

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE(S):We tested the hypothesis that twin pregnancies would lead to increased maternal plasma homocysteine. We further hypothesized that twin pregnancies complicated by preeclampsia would have increased plasma homocysteine compared to twin pregnancies without preeclampsia and normal singleton pregnancies. METHOD...

journal_title：Hypertension in pregnancy

authors： Powers RW,Dunbar MS,Laivuori HM,Harger GF,Lykins DL,Roberts JM

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS:One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were...

journal_title：Hypertension in pregnancy

authors： Lain KY,Krohn MA,Roberts JM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:There is evidence of altered vascular endothelial function in women with preeclampsia as well as in the endothelial cells from umbilical vessels of preeclamptic pregnancies. Matrix metalloproteinase (MMP)-2 is elevated in the plasma of preeclamptic women and is a mediator of vascular reactivity; however, whe...

journal_title：Hypertension in pregnancy

authors： Merchant SJ,Narumiya H,Zhang Y,Guilbert LJ,Davidge ST

更新日期：2004-01-01 00:00:00

abstract：:Preeclampsia and intrauterine growth restriction are both characterized by placental malfunction. The pathological processes of abnormal trophoblast invasion, partial absence of maternal spiral artery modification, increased apoptosis of trophoblast cells, and placental ischemia are all associated with the release of ...

journal_title：Hypertension in pregnancy

authors： Tjoa ML,Oudejans CB,van Vugt JM,Blankenstein MA,van Wijk IJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate the intraplatelet cyclic guanosine-3',5'-monophosphate (cGMP) levels during normal pregnancy and preeclampsia. STUDY DESIGN:Pregnant women (n = 15), women with preeclampsia (n = 15), and nonpregnant, normotensive women (n = 15) were included. Intraplatelet cyclic guanosine-3',5'-monophosphate ...

journal_title：Hypertension in pregnancy

authors： Teran E,Escudero C,Vivero S,Enriquez A,Calle A

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Preeclampsia and intrauterine growth retardation (IUGR) are associated with elevated concentrations of myeloperoxidase (MPO) and polymorphonuclear (PMN) elastase, which indicate maternal neutrophil activation. The aim of the study was to measure maternal MPO and PMN elastase plasma concentrations in second tr...

journal_title：Hypertension in pregnancy

authors： Stepan H,Heihoff-Klose A,Faber R

更新日期：2003-01-01 00:00:00

abstract：:We examined neurological and intellectual outcome of growth-restricted newborns of pregnancies complicated with preeclampsia and without preeclampsia. Seventy-five consecutive growth restricted newborns (<5th percentile) were prospectively followed up at 6 months' intervals. Newborns with major congenital malformation...

journal_title：Hypertension in pregnancy

authors： Many A,Fattal A,Leitner Y,Kupferminc MJ,Harel S,Jaffa A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Trophoblast migration into the maternal circulation is increased in preeclampsia and can trigger the endothelial dysfunction that characterizes the clinical disease. We hypothesised that 'fetal trafficking' is increased in women with severe preeclampsia and that the quantity of trafficking is greater in women...

journal_title：Hypertension in pregnancy

authors： Byrne BM,Crowley A,Taulo F,Anthony J,O'Leary JJ,O'Herlihy C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:We examined serum concentrations of basic fibroblast growth factor (bFGF) in women with hypertensive disorders in pregnancy and analyzed whether serum concentrations of bFGF can be used as a discriminator between mild and severe preeclampsia. METHODS:One hundred and twenty pregnant women were included in thi...

journal_title：Hypertension in pregnancy

authors： Hohlagschwandtner M,Knöfler M,Ploner M,Zeisler H,Joura EA,Husslein P

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Assess the actual rate of eclampsia in Sweden, describe the clinical picture of the disease and the maternal and perinatal outcomes. METHODS:Analysis of data regarding incidence of eclampsia registered in the Swedish Medical Birth Register 1991-1992. The records of all the cases with the diagnosis of eclamps...

journal_title：Hypertension in pregnancy

authors： Kullberg G,Lindeberg S,Hanson U

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to determine if heat shock protein 70 (Hsp 70), a marker of cellular stress, is elevated in pregnancies complicated by severe preeclampsia. METHODS:Maternal blood was collected from women with severe preeclampsia (n=47) matched for delivery gestational age to normotensive pregnan...

journal_title：Hypertension in pregnancy

authors： Livingston JC,Ahokas R,Haddad B,Sibai BM,Awaads R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To provide long-term follow-up data on women with a history of hemolysis, elevated liver enzymes, and low platelets [(H)ELLP] syndrome regarding the risk of recurrence in subsequent pregnancies and disease in later life. METHODS:All women admitted to the Academic Medical Centre between January 1984 and Janua...

journal_title：Hypertension in pregnancy

authors： van Pampus MG,Wolf H,Mayruhu G,Treffers PE,Bleker OP

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To compare connexin expression in omental resistance arteries from preeclamptic women and normal gravidas. METHODS:Small arteries (approximately 200-400 microm i.d.) were dissected from omental fat biopsies, taken at cesarean delivery from normotensive and preeclamptic women. Vessels were frozen and homogeni...

journal_title：Hypertension in pregnancy

authors： Umans JG,Lindheimer MD,Hack B,Davidson-Garcia CA

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To characterize the maternal and fetal presentation of abruptio placentae and associated maternal and fetal morbidity and mortality by mode of delivery and fetal status on admission. STUDY DESIGN:Perinatal data (gestational age > 24 weeks) from women with abruptio placentae at a tertiary referral center were...

journal_title：Hypertension in pregnancy

authors： Witlin AG,Sibai BM

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies. METHODS:We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnanc...

journal_title：Hypertension in pregnancy

authors： Suzuki S,Yoneyama Y,Sawa R,Shin S,Araki T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To examine the management of early-onset preeclampsia and its maternal and fetal morbidity and mortality. DESIGN:Retrospective cohort study of 49,812 births at a university teaching hospital between June 1986 and March 1997. Seventy-one women were identified with a diagnosis of preeclampsia with an onset at ...

journal_title：Hypertension in pregnancy

authors： Murphy DJ,Stirrat GM

更新日期：2000-01-01 00:00:00